Facts About Cinchonain Ib Revealed
Mechanism of Action: Obeticholic acid is an agonist for Farnesoid X Receptor (FXR), a nuclear receptor expressed from the liver and intestine. FXR can be a vital regulator of bile acid, inflammatory, fibrotic and metabolic pathways. FXR activation decreases the intracellular hepatocyte concentrations of bile acids by suppressing de novo synthesis